ncRNA name | hsa-miR-106a |
ncRNA Category | miRNA |
Disease name | diabetic retinopathy (DR) |
Species | Homo sapiens |
Tissues/Cell_line | human RPE cell line ARPE-19 |
Methods | siRNA transfection, qRT-PCR, Western blot, luciferase reporter assay, immunohistochemistry |
Expression pattern | down-regulated |
Functional description | Over-expression of miR-106a significantly reduced the expression of HIF1α and VEGF and prevented high glucose-induced increased permeability. |
PubMed ID | 24018047 |
Year | 2013 |
Title | MicroRNA-dependent cross-talk between VEGF and HIF1α in the diabetic retina. |
Drug-related ncRNA | NO |
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